Northwest Gynecological Cancer Symposium
Monday, December 4th, 2017
8:00 AM – 7:00 PM

PELTON AUDITORIUM | FRED HUTCH | 1100 FAIRVIEW AVE N, SEATTLE, WA 98109

NGCS Invited Speakers

Garnet Anderson

Fred Hutch

Denise Galloway

Fred Hutch

Gordon Mills

Knight Cancer Institute

Brad Nelson

BC Cancer Agency

FULL PROGRAM
The Rivkin Center for Ovarian Cancer is proud to present the 1st biennial Northwest Gynecological Cancer Symposium (NGCS) to be held on Monday, December 4th, 2017 from 8:30am to 6:00pm at Pelton Auditorium at Fred Hutch in Seattle Washington. NGCS is designed to facilitate communication and foster collaboration between scientists in the Pacific Northwest working on the prevention, early detection, and treatment of gynecological cancers. Gynecological cancer-related research areas featured in NGCS include animal models, cancer stem cells, cancer mechanisms, chemoresistance, clinical research, DNA Repair and Response, etiology/pathophysiology, genetics/genomics/epigenetics, immunology, novel therapies, proteomics/metabolomics, tumor microenvironment and more.

Free Registration: The symposium is open to all. The FREE registration is required to partake in catered lunch and reception. Registration is now closed. Email Kiran.Dhillon@swedish.org with questions.

Abstracts: Abstract submission for oral and poster presentations is now closed.

Symposium Location Information: NGCS will be held in Pelton Auditorium located in the Weintraub Building of Fred Hutch at 1100 Fairview Ave, N, Seattle, WA 98109. Pelton Auditorium can be accessed through the main entrance of the Thomas Building. Map

Parking: Fred Hutch offers 2 hours of free visitor parking on a first come, first serve basis. There is also a Diamond parking lot at 1111 Fairview Ave, N which is just a few minutes walk from Fred Hutch.

Questions? Email us at Kiran.Dhillon@swedish.org

NGCS Planning Committee:
Kiran Dhillon, PhD (Rivkin Center for Ovarian Cancer)
Nora Disis, MD (University of Washington, Fred Hutch)
Charles Drescher, MD (Swedish Cancer Institute, Fred Hutch)
Brad Nelson, PhD (British Columbia Cancer Agency)
Rosana Risques, PhD (University of Washington)
Elizabeth Swisher, MD (University of Washington, Seattle Cancer Care Alliance)

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Click To Add12/04/2017 08:30 AM
12/04/2017 07:00 PM
America/Los_Angeles
Northwest Gynecological Cancer Symposium
Pelton Auditorium, Fred Hutch, Seattle, WA
Rivkin Center for Ovarian Cancer
info@rivkin.org
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PROGRAM

8:00am – 8:30am
Check-in & Poster Set-up

8:30am – 8:40am
Opening Remarks by Kiran Dhillon, PhD
Rivkin Center for Ovarian

 

SESSION I: PREVENTION & EARLY DETECTION

8:40am – 8:45am
Intro by Charles Drescher, MD
Swedish Cancer Institute / Fred Hutch

8:45am – 9:00am
Garnet Anderson, PhD (Invited Speaker)
Fred Hutch
Topic: Women’s Health Initiative & LILAC Resources for Gynecological Cancers

9:00am – 9:15am
Van Nghiem, PhD
Fred Hutch
“Look” before you LEEP?  An economic evaluation of the Pap see-and-treat strategy for the management of cervical pre-cancer

9:15am – 9:30am
Shannon Rush, MD
University of Washington
Risk-reducing salpingo-oophorectomy: a single institutional experience in over 500 women at increased risk for ovarian carcinoma

9:30am – 9:45am
Jeffrey Krimmel-Morrison, MD
University of Washington
Deep Sequencing of Pap Smears Reveals Low-Frequency Somatic TP53 Mutations in Women With and Without Serous Ovarian Cancer

9:45am – 10:05am
Panel Discussion & Questions Moderated by Charles Drescher

 

10:05am – 10:30am
COFFEE BREAK

 

SESSION II: CANCER BIOLOGY & MECHANISMS

10:30am – 10:35am
Intro by Rosana Risques, PhD
University of Washington

10:35am – 10:50am
Denise Galloway, PhD (Invited Speaker)
Fred Hutch
HPV oncoproteins disrupt the repair of DNA damage

10:50am – 11:05am
Talayeh Ghezelayagh, MD
University of Washington
Gain-of-function and loss-of-function TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations

11:05am – 11:20am
Maria Isabel Harrell, PhD
University of Washington
Development and implementation of a targeted next generation sequencing methylation panel for the assessment of methylation in ovarian and endometrial cancers

11:20am – 11:35am
Aline Talhouk, PhD
University of British Columbia
Validation of ProMisE molecular classifier in a large population based series:  a new era in endometrial carcinoma diagnosis and treatment

11:35am – 11:50pm
Dawn Cochrane, PhD
British Columbia Cancer Agency
The origins of endometriosis associated cancers

11:50pm – 12:10pm
Panel Discussion & Questions Moderated by Rosana Risques
 

 

SESSION III: SHORT POSTER PRESENTATIONS 1

12:10pm – 12:20pm
Short Poster Presentations

 

12:20pm – 2:00pm
LUNCH & POSTER SESSION

 

SESSION IV: CANCER THERAPY

2:00pm – 2:05pm
Intro by Elizabeth Swisher, MD
University of Washington / Seattle Cancer Care Alliance

2:05pm – 2:20pm
Gordon Mills, MD/PhD (Invited Speaker)
Knight Cancer Institute
Systems approach to rational combination therapy

2:20pm – 2:35pm
Marta Llaurado, PhD
University of British Columbia
Proteomic Biomarkers of MEK inhibitor resistance in low-grade serous ovarian cancer cell lines

2:35pm – 2:50pm
Franz Schaub, PhD
SEngine Precision Medicine
Personalized Medicine: A CLIA-Certified High-Throughput Drug Screening Platform for Ovarian Cancer

2:50pm – 3:05pm
Shary Chen
University of British Columbia
Targeting strategies for small cell hypercalcemic carcinoma of the ovary, hypercalcemic type (SCCOHT)

3:05pm – 3:25pm
Panel Discussion & Questions Moderated by Elizabeth Swisher, MD

 

3:25pm – 3:50pm
COFFEE BREAK
 

 

SESSION V: SHORT POSTER PRESENTATIONS 2

3:50pm – 4:00pm
Short Poster Presentations

 

SESSION VI: IMMUNOTHERAPY

4:00pm – 4:05pm
Intro by Nora Disis, MD
University of Washington / Fred Hutch)

4:05pm – 4:20pm
Brad Nelson, PhD (Invited Speaker)
British Columbia Cancer Agency
Deciphering the immune response to ovarian cancer: the players, strategies, and path forward

4:20pm – 4:35pm
Kristin Anderson, PhD
University of Washington / Fred Hutch
Engineering immunosuppressive pathways operative within T cells for enhancing adoptive therapy of ovarian cancer

4:35pm – 4:50pm
Denise Cecil, PhD
University of Washington
Vaccine targeting antigens associated with epithelial to mesenchymal transition in combination with cisplatin significantly inhibits ovarian cancer growth

4:50pm – 5:05pm
Christopher Morse, MD
University of Washington / Fred Hutch
Adoptive T cell therapy for ovarian cancer: Development of a surgically relevant model

5:05pm – 5:25pm
Panel Discussion & Questions Moderated by Nora Disis, MD

 

5:25pm – 5:30pm
Closing Remarks by Kiran Dhillon, PhD
Rivkin Center for Ovarian Cancer

 

5:30pm – 7:00pm
RECEPTION

 

POSTERS

Michael Anglesio, PhD
University of British Columbia
Advanced Methods for Cancer Detection by Vaginal Screening: feasibility and assessment of deep sequencing based self-sampling methods

Tara Coffin
University of Washington
MAGENTA: a large randomized study to define an optimal genetic counseling strategy in women undergoing genetic testing at home for ovarian cancer risk

Jamie Crase
University of Washington
The Central Role of Advocates on the Stand up To Cancer Ovarian Cancer Research Fund Alliance- National Ovarian Cancer Coalition Ovarian Cancer Dream Team

Soledad Jorge, MD
University of Washington
Disease course and treatment patterns of unselected patients with ovarian carcinoma and germline BRCA mutations

Toni Jun, PhD
Crown Biosciences Inc.
Establishment and characterization of human ovarian cancer xenograft models using bioluminescence imaging

Marilyne Labrie, PhD
Knight Cancer Institute
Adaptive response of ovarian cancer cells to PARP and DNA damage checkpoint inhibitors

Barbara Norquist, MD
University of Washington, Seattle, WA
WISP: a surgical prevention study evaluating bilateral salpingo-oophorectomy versus interval salpingectomy and delayed oophorectomy in women with inherited mutations in ovarian cancer susceptibility genes

Marc Radke
University of Washington
Somatic reversion mutations in hereditary ovarian carcinomas predict platinum sensitivity

Chaoyang Sun, PhD
Knight Cancer Institute
BRD4 inhibition is synthetic lethal with PARP inhibitors through the induction of homologous recombination deficiency

Please note the program is subject to change.

FULL PROGRAM & ABSTRACTS

Accommodations

The symposium will be held at Fred Hutch (Fred Hutchinson Cancer Research Center) at 1100 Fairview Ave NE, Seattle, 98109. We have arranged for a special symposium rate for the Silver Cloud Inn which is adjacent to the Fred Hutch campus. Please note the special rate is available as long as the hotel has availability, on a first come first serve basis.

NGCS Conference Rates:

King or Two Queen Bed Guestroom: $145.00

Lakeview King or Two Queen Bed Guestroom: $165.00

Rates are net and exclusive of tax. Upgraded room types are available at a premium rate and are based on availability.

Online Reservation Instructions
Please click on the GROUP link below:
FHCRC CS

1. On the left hand side of the screen please select the desired arrival and departure dates and input the number of guests.
2. Click on “Search for Availability”
3.
Click on “Reserve” for the room type you prefer.  It will take you to a page where guests can enter all their information.
4. Finally, Click on “Make a Reservation” and your guests should receive a reservation confirmation email shortly thereafter.

Group rates are net, non-commissionable & exclusive of lodging tax.

Please note a $15.00 taxable surcharge is applied for each adult beyond double occupancy. There is a max of (4) four individuals per guestroom, regardless of guestroom type.

Phone Reservation Instructions
Call our hotel directly at 206.447.9500 and ask for the “NW Gynecological Cancer Symposium” or “FHCRC CS” group and a guest services agent will be able to assist with making your reservation.

Hotel Concessions

All guests receive the following complimentary guestroom amenities:

  • Hot Breakfast Daily
  • Wireless High Speed Internet
  • Parking Onsite
  • 24 hr Business Center
  • 24 hr Indoor Pool
  • 24 hr Gift Shop
  • Shuttle Services to Space Needle, Pike Place Market and Pioneer Square

Seattle Transportation Options

 

Parking

Fred Hutch offers 2 hours of free visitor parking on a first come, first serve basis. More Information

There is also a Diamond parking lot at 1111 Fairview Ave, N which is just a few minutes walk from Fred Hutch.

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